Codeine phosphate and guaifenesin

Codeine phosphate and Guaifenesin (Brontex)
Codeine phosphate and guaifenesin
(KOH-deen FOS-fayt, gwye-FEN-eh-sin)

Pregnancy Category | Classification | Contents | Uses | Contraindications | Special Concerns | Side Effects | Overdose Management | Laboratory Test Alterations | Drug Interactions | How Supplied | Dosage
Pregnancy Category
C Brontex (C-III) (Rx)    
Classification

Antitussive/expectorant See Also:

See also Codeine Phosphate and Guaifenesin.

Contents
Antitussive: Codeine phosphate, 10 mg/tablet or 20 mL. Expectorant: Guaifenesin, 300 mg/tablet or 20 mL.
Uses

Relief of cough due to a cold or inhaled irritants. To loosen mucus and thin bronchial secretions.

Contraindications

Asthma, during labor and delivery. Use of tablets in children less than 12 years of age and use of the liquid in children less than 6 years of age.

Special Concerns
Use with caution in clients with severe CNS depression, respiratory depression, acute alcoholism, chronic pulmonary disease, acute abdominal conditions, seizure disorders, fever, hypothyroidism, Addison's disease, ulcerative colitis, prostatic hypertrophy, following recent GI or urinary tract surgery, and in significant renal or hepatic dysfunction, in the very young and elderly, and during lactation.
Side Effects
CNS: CNS depression, lightheadedness, dizziness, sedation, headache, euphoria or dysphoria, transient hallucinations, disorientation, visual disturbances, seizures. CV: Tachycardia, bradycardia, palpitations, syncope, faintness, orthostatic hypotension, circulatory depression. GI: N&V, stomach pain, constipation, biliary tract spasm, increased colonic motility in those with ulcerative colitis. GU: Oliguria, urinary retention. Allergic: Pruritus, urticaria, angioneurotic edema, laryngeal edema, anaphylaxis. Miscellaneous: Flushing of the face, sweating, weakness.
Overdose Management
 
Laboratory Test Alterations
None.
Drug Interactions
Additive CNS depression if used with alcohol, sedatives, antianxiety agents, and MAO inhibitors
How supplied
See Content
Dosage
  • Oral Solution, Tablets Cough/colds, bronchial congestion. Adults and children over 12 years of age: One tablet q 4 hr or 20 mL (4 teaspoonfuls) q 4 hr. Children, 6-12 years of age: 10 mL (2 teaspoonfuls) q 4 hr.